SCHEMBL9850138

SCHEMBL9850138

CCCC[Si](C)(C)OCCCCC(C(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.38
FFAR1 O14842 1/20 0.38
MAPT P10636 1/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
CA2 P00918 1/20 0.35
MAPK1 P28482 1/20 0.35
ACE2 Q9BYF1 1/20 0.35
GRIK1 P39086 2/20 0.33
GRIK2 Q13002 2/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
FFAR4 Q5NUL3 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2578863 0.78 GPR84 (0.53) GPR84FFAR1MAPTPPARDFFAR4
SCHEMBL8161878 0.78 CA1 (0.33) MAPTCA2
SCHEMBL5695221 0.77 AKR1B1 (0.48) GPR84FFAR1MAPTPPARDFFAR4
SCHEMBL1742905 0.77 GPR84 (0.36) GPR84FFAR1FFAR4
SCHEMBL15292867 0.75 ADRB2 (0.38) CA2
SCHEMBL8896843 0.74 SMN1; SMN2 (0.44) MAPTACHE
Fluoride SCHEMBL28805747 0.73 ADRB2 (0.36) CA2
SCHEMBL15984917 0.73 CA1 (0.33) MAPTCA2
SCHEMBL268595 0.73 GPR84 (0.62) GPR84FFAR1MAPTLCKPPARD
SCHEMBL7539080 0.73 LMNA (0.46) MAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409066-A2 Optically active compound for liquid crystal and its use MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-01-23 EP disclosed