Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850695 | 0.84 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9850510 | 0.83 | MEN1 (0.43) | BCHEALDH1A1RECQLKDM4EMAPT | |
| SCHEMBL9850498 | 0.78 | BCHE (0.49) | BCHECA12CA4CA7CA9 | |
| Hydrochloric Acid SCHEMBL9850536 | 0.78 | ALDH1A1 (0.70) | BCHECA12CA4CA7CA9 | |
| SCHEMBL10837351 | 0.76 | CA12 (0.44) | CA12CA4CA7CA9CA14 | |
| SCHEMBL11283741 | 0.74 | CA12 (0.77) | BCHECA12CA4CA7CA9 | |
| Hydrochloric Acid SCHEMBL9850592 | 0.73 | BCHE (0.52) | BCHECA12CA4CA7CA9 | |
| Hydrochloric Acid SCHEMBL4443499 | 0.73 | ALDH1A1 (0.78) | BCHECA12CA4CA7CA9 | |
| SCHEMBL9850566 | 0.72 | NPC1 (0.55) | BCHECA12CA4CA7CA9 | |
| Hydrochloric Acid SCHEMBL9850546 | 0.71 | ALDH1A1 (0.60) | BCHECA12CA4CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |