Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850313 | 0.83 | BCHE (0.47) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9850493 | 0.82 | MEN1 (0.52) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL522650 | 0.80 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9850419 | 0.80 | JAK2 (0.44) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9850695 | 0.78 | HTR1A (0.58) | CYP1A2 | |
| SCHEMBL9850257 | 0.77 | MEN1 (0.51) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9850386 | 0.76 | MEN1 (0.64) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9850488 | 0.76 | MAPT (0.54) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL10837351 | 0.75 | CA12 (0.44) | MAPTALDH1A1RECQL | |
| Hydrochloric Acid SCHEMBL9850592 | 0.75 | BCHE (0.52) | MEN1KMT2AMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |