Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19452382 | 0.89 | TDP1 (0.48) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL8896071 | 0.85 | ALDH1A1 (0.69) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL9066833 | 0.84 | TDP1 (0.43) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL43962 | 0.83 | TDP1 (0.72) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL10985472 | 0.80 | ALDH1A1 (0.62) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL27601087 | 0.80 | ALDH1A1 (0.62) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL95780 | 0.80 | ADRB2 (0.49) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL29498969 | 0.80 | ADRB2 (0.49) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL9850296 | 0.80 | TDP1 (0.46) | TDP1ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL15902738 | 0.80 | ADRB2 (0.49) | TDP1ALDH1A1TSHRHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444604-A2 | Crosslinking of fluorrubber via crosslinking initiators not forming any methyl- or phenyl-radicals | Elf Atochem Deutschland GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |