Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19452382 | 0.90 | TDP1 (0.48) | TDP1ALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL9066833 | 0.88 | TDP1 (0.43) | TDP1ALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL659618 | 0.85 | TDP1 (0.59) | TDP1ALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL2884831 | 0.83 | ALDH1A1 (0.55) | TDP1ALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL9067159 | 0.82 | ADRB2 (0.45) | TDP1ALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL13948367 | 0.80 | TDP1 (0.52) | TDP1ALDH1A1GAAKMT2ARAB9A | |
| SCHEMBL9850336 | 0.80 | TDP1 (0.52) | TDP1ALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL11683963 | 0.76 | ALDH1A1 (0.31) | TDP1ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL8896071 | 0.75 | ALDH1A1 (0.69) | TDP1ALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL28283385 | 0.75 | LMNA (0.54) | TDP1ALDH1A1TSHRHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444604-A2 | Crosslinking of fluorrubber via crosslinking initiators not forming any methyl- or phenyl-radicals | Elf Atochem Deutschland GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |