Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625972 | 0.83 | CYP3A4 (0.56) | LMNACES2CES1MAPK1RECQL | |
| SCHEMBL30497869 | 0.83 | LMNA (0.46) | LMNACES2CES1MAPK1RECQL | |
| SCHEMBL11224343 | 0.82 | LMNA (0.55) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL11378946 | 0.81 | LMNA (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL11383664 | 0.81 | LMNA (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL27939668 | 0.81 | CES2 (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL22807498 | 0.81 | POLB (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL17956727 | 0.81 | ALDH1A1 (0.55) | LMNACES2CES1MAPK1RECQL | |
| SCHEMBL461654 | 0.80 | LMNA (0.57) | LMNACES2CES1MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30785538 | 0.78 | LMNA (0.55) | LMNACES2CES1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433112-A1 | Modified gangliosides and the functional derivatives thereof | FIDIA S.p.A. (IT) | 1991-06-19 | — | — | EP | disclosed |