Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MDM4 | O15151 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | NSD2 | O96028 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113791 | 0.81 | PDE10A (0.67) | PDE10AKMT2ANFKBIARELAMEN1 | |
| SCHEMBL30345050 | 0.81 | NPC1 (0.72) | PDE10AKMT2ANFKBIARELAMEN1 | |
| SCHEMBL23997427 | 0.81 | NPC1 (0.72) | PDE10AKMT2ANFKBIARELAMEN1 | |
| Hydrochloric Acid SCHEMBL9850493 | 0.81 | MEN1 (0.52) | KMT2ANFKBIAMEN1SLC40A1TDP1 | |
| SCHEMBL9850428 | 0.80 | ALDH1A1 (0.60) | KMT2AMEN1MAPTKAT2BNPC1 | |
| SCHEMBL522650 | 0.79 | MEN1 (0.59) | KMT2ANFKBIAMEN1SLC40A1TDP1 | |
| SCHEMBL9850257 | 0.79 | MEN1 (0.51) | KMT2ANFKBIAMEN1SLC40A1TDP1 | |
| SCHEMBL9850488 | 0.78 | MAPT (0.54) | KMT2ANFKBIAMEN1OPRK1SLC40A1 | |
| SCHEMBL9850386 | 0.78 | MEN1 (0.64) | KMT2ARELAMEN1TDP1MAPT | |
| SCHEMBL6198859 | 0.78 | KAT2B (0.80) | KMT2AMEN1TDP1MAPTKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |