Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198859 | 0.83 | KAT2B (0.80) | ALDH1A1MAPTMEN1KMT2AKAT2B | |
| Hydrochloric Acid SCHEMBL9850536 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9850357 | 0.80 | PDE10A (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9850487 | 0.80 | HTR1A (0.62) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4940897 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL11283741 | 0.78 | CA12 (0.77) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| Ammonia Solution, Strong SCHEMBL27766738 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1470938 | 0.77 | KAT2B (0.61) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6200169 | 0.76 | KAT2B (0.81) | ALDH1A1MAPTMEN1KMT2AKAT2B | |
| SCHEMBL7170020 | 0.76 | KAT2B (0.81) | ALDH1A1MAPTMEN1KMT2AKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |