Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.50 |
| ▸ | RARA | P10276 | 6/20 | 0.50 |
| ▸ | RARG | P13631 | 4/20 | 0.50 |
| ▸ | RXRA | P19793 | 4/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850174 | 0.93 | RARB (0.48) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9850261 | 0.93 | RARB (0.53) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9850221 | 0.91 | RARA (0.54) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9850106 | 0.90 | RXRA (0.48) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9850125 | 0.86 | RARB (0.55) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9850240 | 0.85 | RARA (0.52) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9850280 | 0.84 | RXRA (0.41) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL9850253 | 0.84 | RXRA (0.49) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9850172 | 0.84 | RXRA (0.46) | RARBRARARARGRXRAHNF4A | |
| SCHEMBL9850185 | 0.84 | RARA (0.56) | RARBRARARARGRXRAHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |