Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | RARA | P10276 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850140 | 0.93 | MAPT (0.41) | RXRARARBRARACYP3A4KMT2A | |
| SCHEMBL9850216 | 0.91 | RARA (0.49) | RXRARARBRARAKMT2AALDH1A1 | |
| SCHEMBL9850214 | 0.91 | RXRA (0.52) | RXRARARBRARARARG | |
| SCHEMBL9850094 | 0.90 | MAPT (0.43) | RXRARARBRARAKMT2AALDH1A1 | |
| SCHEMBL9850223 | 0.86 | HIF1A (0.42) | RXRARARBRARACYP3A4KMT2A | |
| SCHEMBL9850236 | 0.86 | RARB (0.45) | RARBRARACYP3A4KMT2AALDH1A1 | |
| SCHEMBL9850095 | 0.85 | RARA (0.47) | RXRARARBRARAKMT2AALDH1A1 | |
| SCHEMBL9850227 | 0.85 | RXRA (0.48) | RXRARARBRARATSHR | |
| SCHEMBL9850358 | 0.84 | RARB (0.50) | RXRARARBRARACYP3A4KMT2A | |
| SCHEMBL9850263 | 0.84 | MAPT (0.45) | RXRARARBRARACYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |