SCHEMBL9850360

SCHEMBL9850360

c1cnnc(NCCNCCNc2cccc3ccccc23)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.49
CA12 O43570 2/20 0.49
CA4 P22748 2/20 0.49
CA7 P43166 2/20 0.49
CA9 Q16790 2/20 0.49
CA14 Q9ULX7 2/20 0.49
CA3 P07451 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49
CA5B Q9Y2D0 1/20 0.49
ALDH1A1 P00352 4/20 0.48
TSHR P16473 2/20 0.48
HSD17B10 Q99714 2/20 0.48
RECQL P46063 1/20 0.48
MAPT P10636 4/20 0.46
KDM4E B2RXH2 3/20 0.46
HPGD P15428 2/20 0.46
GAA P10253 1/20 0.46
HTR1A P08908 2/20 0.39
ADRA1D P25100 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9850431 0.83 BCHE (0.54) BCHECA12CA4CA7CA9
Hydrochloric Acid SCHEMBL9850536 0.80 ALDH1A1 (0.70) BCHECA12CA4CA7CA9
SCHEMBL9850446 0.80 BCHE (0.48) BCHECA12CA4CA7CA9
SCHEMBL9850580 0.77 BCHE (0.48) BCHECA12CA4CA7CA9
SCHEMBL11283741 0.76 CA12 (0.77) BCHECA12CA4CA7CA9
Hydrochloric Acid SCHEMBL9850592 0.75 BCHE (0.52) BCHECA12CA4CA7CA9
SCHEMBL9850624 0.75 ALDH1A1 (0.46) ALDH1A1HSD17B10MAPTKDM4EHPGD
Hydrochloric Acid SCHEMBL4443499 0.75 ALDH1A1 (0.78) BCHECA12CA4CA7CA9
SCHEMBL9850459 0.74 CA12 (0.51) BCHECA12CA4CA7CA9
SCHEMBL9850407 0.74 HTR1A (0.73) BCHECA12CA4CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443862-A1 Triamine derivatives and their acid-addition salts SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1991-08-28 EP disclosed