Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.73 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.73 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850466 | 0.91 | HTR1A (0.89) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850499 | 0.88 | HTR1A (0.64) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850708 | 0.87 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850475 | 0.86 | CCNC (0.62) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850457 | 0.86 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850591 | 0.84 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850606 | 0.84 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850509 | 0.83 | HTR1A (0.66) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850459 | 0.82 | CA12 (0.51) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| Hydrochloric Acid SCHEMBL9850536 | 0.82 | ALDH1A1 (0.70) | HTR1AADRA1DADRA1AADRA1BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |