Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850466 | 0.82 | HTR1A (0.89) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| Hydrochloric Acid SCHEMBL9850654 | 0.80 | HTT (0.55) | HTTSMN1; SMN2NPSR1 | |
| SCHEMBL9850407 | 0.79 | HTR1A (0.73) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850606 | 0.78 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850354 | 0.76 | HTT (0.48) | HTTSMN1; SMN2NPSR1 | |
| SCHEMBL9850591 | 0.76 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850330 | 0.76 | HTT (0.49) | ACHEHTTSMN1; SMN2NPSR1 | |
| SCHEMBL9850572 | 0.75 | HTR1A (0.66) | HTR1AADRA1DADRA1AADRA1BACHE | |
| SCHEMBL9850499 | 0.74 | HTR1A (0.64) | HTR1AADRA1DADRA1AADRA1BACHE | |
| SCHEMBL22390094 | 0.73 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |