Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9850654 | 0.82 | HTT (0.55) | HTTSMN1; SMN2NPSR1RXRARXRB | |
| Hydrochloric Acid SCHEMBL9850493 | 0.81 | MEN1 (0.52) | HTTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL522650 | 0.79 | MEN1 (0.59) | HTTSMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL9850488 | 0.78 | MAPT (0.54) | HTTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9850257 | 0.76 | MEN1 (0.51) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9850384 | 0.76 | HTR1A (0.59) | HTTSMN1; SMN2NPSR1ACHE | |
| SCHEMBL9850506 | 0.75 | HTR1A (0.48) | HTTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9850354 | 0.75 | HTT (0.48) | HTTSMN1; SMN2NPSR1RXRARXRB | |
| SCHEMBL9850386 | 0.75 | MEN1 (0.64) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9850394 | 0.74 | SLC40A1 (0.55) | HTTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |