Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.62 |
| ▸ | CDK8 | P49336 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850407 | 0.86 | HTR1A (0.73) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850497 | 0.85 | CYP1A2 (0.57) | CCNCCDK8CYP1A2KDM4EALDH1A1 | |
| SCHEMBL9850457 | 0.78 | HTR1A (0.71) | CYP1A2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL18962393 | 0.77 | CYP1A2 (0.91) | CYP1A2CCR1FERMT2PKMKDM4E | |
| SCHEMBL30402656 | 0.77 | CYP1A2 (0.91) | CYP1A2CCR1FERMT2PKMKDM4E | |
| SCHEMBL15483248 | 0.77 | CYP1A2 (0.91) | CYP1A2CCR1FERMT2PKMKDM4E | |
| SCHEMBL21750458 | 0.77 | CCNC (1.00) | CCNCCDK8CYP1A2HTR1AADRA1D | |
| SCHEMBL9850466 | 0.77 | HTR1A (0.89) | CYP1A2HTR1AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9850339 | 0.76 | FADS1 (0.60) | PKMKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9850499 | 0.75 | HTR1A (0.64) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |