Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850506 | 0.85 | HTR1A (0.48) | ALDH1A1KDM4EHPGDHTR1AADRA1D | |
| SCHEMBL9850716 | 0.84 | BCHE (0.47) | ALDH1A1KDM4EHPGDHTR1AADRA1D | |
| SCHEMBL9850448 | 0.84 | ADRA1A (0.53) | ALDH1A1KDM4EHPGDHTR1AADRA1D | |
| SCHEMBL9850459 | 0.83 | CA12 (0.51) | ALDH1A1KDM4EHPGDHTR1AADRA1D | |
| SCHEMBL9850321 | 0.83 | MAPT (0.63) | ALDH1A1KDM4EHPGDHTR1AADRA1D | |
| SCHEMBL9850379 | 0.81 | NPC1 (0.46) | ALDH1A1KDM4EHPGDHTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL9850592 | 0.78 | BCHE (0.52) | ALDH1A1KDM4EHPGDHTR1AADRA1D | |
| SCHEMBL9850383 | 0.78 | KMT2A (0.46) | ALDH1A1KDM4EHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9850431 | 0.78 | BCHE (0.54) | ALDH1A1KDM4EHPGDHTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL9850536 | 0.78 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |