SCHEMBL9850669

SCHEMBL9850669

CCc1ccc(C(=O)Cc2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.65
MAPT P10636 1/20 0.65
SRD5A2 P31213 2/20 0.62
ALDH1A1 P00352 2/20 0.59
TP53 P04637 1/20 0.54
STS P08842 1/20 0.53
S1PR5 Q9H228 1/20 0.53
GRM1 Q13255 1/20 0.52
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
PLAU P00749 2/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.49
KDM4E B2RXH2 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 1/20 0.49
PLK1 P53350 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919749 0.94 MAPT (0.56) L3MBTL1MAPTSRD5A2ALDH1A1TP53
SCHEMBL12566040 0.92 ALDH1A1 (0.61) L3MBTL1MAPTSRD5A2ALDH1A1NPC1
SCHEMBL7129800 0.88 MAPT (0.80) L3MBTL1MAPTSRD5A2STSS1PR5
SCHEMBL12065143 0.85 L3MBTL1 (0.62) L3MBTL1MAPTSRD5A2ALDH1A1STS
Butane SCHEMBL4453322 0.84 MAPT (0.63) L3MBTL1MAPTSRD5A2ALDH1A1STS
SCHEMBL11635179 0.84 L3MBTL1 (0.69) L3MBTL1MAPTSRD5A2STSS1PR5
Alcohol SCHEMBL11084219 0.84 MAPT (0.63) L3MBTL1MAPTSRD5A2ALDH1A1STS
Methyl Alcohol SCHEMBL11602292 0.84 MAPT (0.68) L3MBTL1MAPTSRD5A2ALDH1A1STS
SCHEMBL7199268 0.83 MAPT (0.67) L3MBTL1MAPTSRD5A2ALDH1A1STS
SCHEMBL24800 0.83 MAPT (0.73) L3MBTL1MAPTSRD5A2ALDH1A1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113755862-B Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2022-08-19 CN claimed
CN-113755862-A Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2021-12-07 CN claimed
CN-118908819-B Preparation method of organic ketone compound under synergistic catalysis of light and metal 延安大学 2025-04-18 CN disclosed
CN-118908819-A Preparation method of organic ketone compound under synergistic catalysis of light and metal 延安大学 2024-11-08 CN disclosed
CN-113755862-B Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2022-08-19 CN disclosed
CN-113755862-A Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2021-12-07 CN disclosed
CN-106547168-B Black matrix material composition and application 深圳市华星光电技术有限公司 2020-09-01 CN disclosed
US-8293715-B2 10a-Azalide compound crosslinked at 10a- and 12-positions TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-10-23 US disclosed
US-20110237784-A1 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2011-09-29 US disclosed
EP-0423524-A2 Propiophenone derivatives and their preparation and pharmaceutical use MARUHO Co., Ltd. (JP) 1991-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237784-A1 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS DCLRE1A, AZI2, CHD9 L3MBTL1 2750/4885MAPT 4511/4885SRD5A2 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.