Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.66 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.51 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850466 | 0.86 | HTR1A (0.89) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850606 | 0.82 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL7504019 | 0.82 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL15923066 | 0.82 | HTR1A (0.65) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850407 | 0.81 | HTR1A (0.73) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL30307397 | 0.80 | GAK (0.66) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL19283173 | 0.80 | GAK (0.66) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL9850591 | 0.80 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850473 | 0.79 | CHRM2 (0.59) | HTR1AADRA1DADRA1AADRA1BCHRM2 | |
| SCHEMBL15923436 | 0.77 | HTR1A (0.73) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |