Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 3/20 | 0.66 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.66 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.66 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283173 | 1.00 | GAK (0.66) | GAKRIPK2COQ8ANLKHTT | |
| SCHEMBL21346887 | 0.83 | POLB (0.77) | GAKRIPK2COQ8ANLKPOLB | |
| SCHEMBL6752938 | 0.83 | HTR1A (0.68) | GAKRIPK2COQ8ANLKHTT | |
| SCHEMBL15923397 | 0.82 | ERBB2 (0.68) | GAKRIPK2COQ8ANLKHTT | |
| SCHEMBL31197392 | 0.82 | ERBB2 (0.68) | GAKRIPK2COQ8ANLKHTT | |
| SCHEMBL19283194 | 0.81 | C1R (0.53) | GAKRIPK2COQ8ANLKHTT | |
| SCHEMBL2980684 | 0.81 | GAK (0.58) | GAKRIPK2COQ8ANLKHTT | |
| SCHEMBL9850697 | 0.80 | HTR1A (0.66) | GAKRIPK2COQ8ANLKHTT | |
| SCHEMBL15923896 | 0.80 | POLB (0.52) | GAKRIPK2COQ8ANLKHTT | |
| SCHEMBL15923433 | 0.79 | POLB (0.55) | GAKRIPK2COQ8ANLKHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947684-A | Method for preparing 4-aminoquinoline derivatives through palladium and copper concerted catalytic oxidation aromatization | 贵州医科大学 | 2023-04-11 | — | — | CN | disclosed |