Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287324 | 0.91 | KMT2A (0.39) | KMT2ATSHRMAPTGAAALOX5 | |
| SCHEMBL149491 | 0.81 | TSHR (0.42) | KMT2ATSHRMAPTGAAALOX5 | |
| SCHEMBL15063441 | 0.75 | KMT2A (0.37) | KMT2ATSHRMAPTGAAALOX5 | |
| SCHEMBL10788267 | 0.74 | EPHX1 (0.42) | KMT2ATSHRMAPTGAAALDH1A1 | |
| SCHEMBL28846577 | 0.74 | KMT2A (0.36) | KMT2ATSHRMAPTGAAALOX5 | |
| SCHEMBL15063335 | 0.74 | NPSR1 (0.38) | KMT2ATSHRMAPTGAAALOX5 | |
| SCHEMBL10787743 | 0.71 | TSHR (0.42) | KMT2ATSHRMAPTGAAALDH1A1 | |
| SCHEMBL10998222 | 0.71 | TSHR (0.42) | KMT2ATSHRMAPTGAAALDH1A1 | |
| SCHEMBL11097238 | 0.70 | TSHR (0.40) | KMT2ATSHRMAPTGAAALOX5 | |
| SCHEMBL233879 | 0.70 | TSHR (0.40) | TSHRMAPTGAAALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405786-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-02 | — | — | EP | disclosed |