SCHEMBL6287324

SCHEMBL6287324

CCC[Si](CC)(CC)Nc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.36
MAPT P10636 3/20 0.35
GAA P10253 2/20 0.35
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 5/20 0.35
EPHX1 P07099 3/20 0.35
HTT P42858 1/20 0.35
KCNH3 Q9ULD8 1/20 0.35
ALOX12 P18054 1/20 0.35
HPGD P15428 2/20 0.34
NPSR1 Q6W5P4 2/20 0.33
CTSD P07339 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9850860 0.91 KMT2A (0.41) KMT2ATSHRMAPTGAAALOX5
SCHEMBL149491 0.87 TSHR (0.42) KMT2ATSHRMAPTGAAALOX5
SCHEMBL10787743 0.73 TSHR (0.42) KMT2ATSHRMAPTGAAALDH1A1
SCHEMBL10998222 0.73 TSHR (0.42) KMT2ATSHRMAPTGAAALDH1A1
SCHEMBL15063441 0.72 KMT2A (0.37) KMT2ATSHRMAPTGAAALOX5
SCHEMBL11097238 0.71 TSHR (0.40) KMT2ATSHRMAPTGAAALOX5
SCHEMBL10788267 0.71 EPHX1 (0.42) KMT2ATSHRMAPTGAAALDH1A1
SCHEMBL28846577 0.71 KMT2A (0.36) KMT2ATSHRMAPTGAAALOX5
SCHEMBL15063335 0.71 NPSR1 (0.38) KMT2ATSHRMAPTGAAALOX5
SCHEMBL233879 0.67 TSHR (0.40) TSHRMAPTGAAALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919291-B2 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-07-19 US disclosed
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US disclosed
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization FZD7, FOS, COG4 KMT2A 2997/4885TSHR 4247/4885MAPT 349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.