SCHEMBL15063441

SCHEMBL15063441

CCC[Si](Nc1ccccc1)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.37
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
GAA P10253 4/20 0.33
EPHX1 P07099 3/20 0.33
MAPT P10636 3/20 0.33
KCNH3 Q9ULD8 2/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
ALOX5 P09917 1/20 0.33
ALOX12 P18054 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28548128 0.84 NPSR1 (0.37) HPGDNPSR1GAAMAPTKCNH3
SCHEMBL15063335 0.83 NPSR1 (0.38) KMT2AHPGDNPSR1GAAEPHX1
SCHEMBL28846577 0.79 KMT2A (0.36) KMT2AHPGDNPSR1GAAEPHX1
SCHEMBL9850860 0.75 KMT2A (0.41) KMT2AHPGDNPSR1GAAEPHX1
Diphenylamine SCHEMBL28718278 0.73 HSD17B10 (0.46) KMT2AHPGDNPSR1GAAMAPT
SCHEMBL6287324 0.72 KMT2A (0.39) KMT2AHPGDNPSR1GAAEPHX1
Diphenylamine SCHEMBL29183344 0.72 HSD17B10 (0.44) KMT2AHPGDNPSR1GAAMAPT
SCHEMBL28121455 0.71 NPSR1 (0.40) KMT2AHPGDNPSR1GAAMAPT
SCHEMBL1856484 0.70 TDP1 (0.42) KMT2AHPGDMAPTKCNH3TSHR
SCHEMBL11097238 0.69 TSHR (0.40) KMT2AHPGDNPSR1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104673170-A Long-opening-time primer and preparation method thereof Beijing tianshan new material technology co ltd 2015-06-03 CN claimed
US-20260048880-A1 HIGH EFFICIENCY PHARMACEUTICAL FILLING LINE CORNING INC (US) 2026-02-19 US disclosed
EP-3959180-B1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYSILAZANE CORNING INC (US) 2025-10-15 EP disclosed
US-12409103-B2 Glass articles with low-friction coatings CORNING INCORPORATED (US) 2025-09-09 US disclosed
US-12391600-B2 Delamination resistant glass containers with heat-tolerant coatings CORNING INCORPORATED (US) 2025-08-19 US disclosed
US-12365498-B2 High efficiency pharmaceutical filling line CORNING INCORPORATED (US) 2025-07-22 US disclosed
EP-4444665-A1 CHEMICALLY DURABLE BOROSILICATE GLASS COMPOSITIONS FOR STORING PHARMACEUTICAL COMPOSITIONS AND ARTICLES FORMED THEREFROM Corning Incorporated (US) 2024-10-16 EP disclosed
CN-118541334-A Chemically durable borosilicate glass compositions for storage of pharmaceutical compositions and articles formed therefrom 康宁股份有限公司 2024-08-23 CN disclosed
US-20240225956-A1 GLASS CONTAINERS WITH DELAMINATION RESISTANCE AND IMPROVED DAMAGE TOLERANCE CORNING INCORPORATED (US) 2024-07-11 US disclosed
US-20240197566-A1 GLASS CONTAINERS WITH IMPROVED STRENGTH AND IMPROVED DAMAGE TOLERANCE CORNING INCORPORATED (US) 2024-06-20 US disclosed
WO-2014085246-A1 GLASS CONTAINERS WITH DELAMINATION RESISTANCE AND IMPROVED DAMAGE TOLERANCE CORNING INCORPORATED (US) 2014-06-05 WO disclosed
US-20140151371-A1 GLASS CONTAINERS WITH DELAMINATION RESISTANCE AND IMPROVED STRENGTH CORNING INCORPORATED (US) 2014-06-05 US disclosed
US-20140069886-A1 DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS CORNING INCORPORATED (US) 2014-03-13 US disclosed
US-20140034544-A1 STRENGTHENED BOROSILICATE GLASS CONTAINERS WITH IMPROVED DAMAGE TOLERANCE CORNING INCORPORATED (US) 2014-02-06 US disclosed
WO-2014005030-A1 DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS CORNING INCORPORATED (US) 2014-01-03 WO disclosed
US-20140001143-A1 DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS CORNING INCORPORATED 2014-01-02 US disclosed
US-20140001076-A1 DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS CORNING INCORPORATED (US) 2014-01-02 US disclosed
WO-2013130724-A2 GLASS ARTICLES WITH LOW-FRICTION COATINGS CORNING INCORPORATED (US) 2013-09-06 WO disclosed
US-20130224407-A1 Glass Articles With Low-Friction Coatings CORNING INCORPORATED (US) 2013-08-29 US disclosed
US-20130171456-A1 Glass Articles With Low-Friction Coatings CORNING INCORPORATED (US) 2013-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048880-A1 HIGH EFFICIENCY PHARMACEUTICAL FILLING LINE HTR2B, P2RY10, P2RX4 KMT2A 3956/4885HPGD 4445/4885NPSR1 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.