Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13542699 | 0.84 | ATM (0.55) | ATMHSP90AA1ANPEPPOLBNPSR1 | |
| SCHEMBL12994766 | 0.81 | ATM (0.55) | ATMHSP90AA1ANPEPPOLBNPSR1 | |
| Benzene SCHEMBL9851001 | 0.81 | ANPEP (0.51) | ANPEPPOLBNPSR1LMNAHTT | |
| SCHEMBL12832472 | 0.78 | ATM (0.60) | ATMHSP90AA1ANPEPPOLBNPSR1 | |
| SCHEMBL9594586 | 0.77 | HDAC4 (0.43) | LMNASMN1; SMN2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL9222065 | 0.77 | HSD17B10 (0.59) | ATMHSP90AA1POLBNPSR1LMNA | |
| SCHEMBL6356591 | 0.77 | ATM (0.58) | ATMHSP90AA1ANPEPPOLBNPSR1 | |
| SCHEMBL11781761 | 0.77 | ATM (0.51) | ATMHSP90AA1ANPEPPOLBNPSR1 | |
| SCHEMBL9678826 | 0.76 | CTSS (0.59) | ATMHSP90AA1L3MBTL1SCN9A | |
| SCHEMBL11415968 | 0.76 | CTSK (0.56) | ATMLMNAL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |