Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521753 | 0.81 | ANPEP (0.56) | ANPEPHTTCYP2C19ALOX15TSHR | |
| Benzene SCHEMBL9850973 | 0.81 | ATM (0.55) | ANPEPHTTCYP2C19ALOX15ALDH1A1 | |
| SCHEMBL9679671 | 0.79 | CTSS (0.58) | HTT | |
| SCHEMBL4338457 | 0.77 | CYP2C19 (0.54) | ANPEPHTTCYP2C19ALOX15TSHR | |
| SCHEMBL9546432 | 0.77 | ANPEP (0.52) | ANPEPHTTCYP2C19ALOX15TSHR | |
| SCHEMBL6902097 | 0.77 | ANPEP (0.52) | ANPEPHTTCYP2C19ALOX15TSHR | |
| SCHEMBL11415356 | 0.77 | ANPEP (0.52) | ANPEPHTTCYP2C19ALOX15TSHR | |
| Ammonia Solution, Strong SCHEMBL11142977 | 0.76 | CYP2C19 (0.53) | ANPEPHTTCYP2C19ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL8974932 | 0.76 | ANPEP (0.51) | ANPEPHTTCYP2C19ALOX15TSHR | |
| SCHEMBL9222065 | 0.75 | HSD17B10 (0.59) | HTTALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |