Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | PAM | P19021 | 1/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.48 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.48 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678826 | 0.85 | CTSS (0.59) | CTSSCTSKPAMGNPATPSMB8 | |
| SCHEMBL9679677 | 0.83 | SOAT2 (0.57) | CTSSCTSKPAMGNPATPSMB8 | |
| SCHEMBL14113860 | 0.79 | CTSS (0.74) | CTSSCTSKPAMGNPATSCN9A | |
| Benzene SCHEMBL9851001 | 0.79 | ANPEP (0.51) | HTT | |
| SCHEMBL23376600 | 0.78 | CTSS (0.68) | CTSSCTSKPAMGNPATTACR1 | |
| SCHEMBL13956933 | 0.78 | CTSS (0.68) | CTSSCTSKPAMGNPATTACR1 | |
| SCHEMBL4436239 | 0.78 | CTSS (0.68) | CTSSCTSKPAMGNPATTACR1 | |
| SCHEMBL1081111 | 0.77 | GNPAT (0.73) | CTSSCTSKPAMGNPAT | |
| SCHEMBL6677690 | 0.77 | GNPAT (0.73) | CTSSCTSKPAMGNPAT | |
| SCHEMBL5692056 | 0.77 | GNPAT (0.73) | CTSSCTSKPAMGNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |