SCHEMBL9851131

SCHEMBL9851131

Nc1c(C(=O)O)cccc1-c1cccc(C(=O)O)c1N

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.65
CASP7 P55210 1/20 0.65
CASP6 P55212 1/20 0.65
HSD17B10 Q99714 2/20 0.54
MMP2 P08253 1/20 0.54
MYC P01106 1/20 0.53
ALDH1A1 P00352 7/20 0.52
ALOX15 P16050 1/20 0.52
MAPT P10636 3/20 0.52
LMNA P02545 2/20 0.52
MEN1 O00255 2/20 0.52
THRB P10828 2/20 0.52
MAPK1 P28482 2/20 0.52
KMT2A Q03164 2/20 0.52
POLB P06746 1/20 0.52
RECQL P46063 1/20 0.52
HNF4A P41235 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.48
NAPRT Q6XQN6 2/20 0.47
KDM4E B2RXH2 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744802 0.96 G6PD (0.61) G6PDCASP7CASP6HSD17B10MMP2
SCHEMBL6316176 0.90 G6PD (0.55) G6PDCASP7CASP6HSD17B10MMP2
SCHEMBL17744826 0.89 G6PD (0.59) G6PDCASP7CASP6HSD17B10MMP2
SCHEMBL15060465 0.88 G6PD (0.69) G6PDCASP7CASP6HSD17B10MMP2
SCHEMBL29386467 0.88 G6PD (0.69) G6PDCASP7CASP6HSD17B10MMP2
SCHEMBL526919 0.87 G6PD (0.74) G6PDCASP7CASP6HSD17B10MMP2
SCHEMBL758071 0.87 HNF4A (0.63) G6PDCASP7CASP6HSD17B10MMP2
SCHEMBL4256428 0.87 ALB (0.52) G6PDCASP7CASP6HSD17B10MMP2
SCHEMBL4249094 0.87 ALDH1A1 (0.57) G6PDCASP7CASP6MYCALDH1A1
SCHEMBL3824312 0.87 MYC (0.66) G6PDCASP7CASP6HSD17B10MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424940-A2 Positive photosensitive polyimide resin composition NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-05-02 EP disclosed