SCHEMBL9851274

SCHEMBL9851274

Fc1cccc(Oc2ccc[nH]2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.40
SLC6A4 P31645 6/20 0.40
SLC6A3 Q01959 5/20 0.40
HTR1A P08908 3/20 0.40
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
ERBB3 P21860 1/20 0.38
ERBB4 Q15303 1/20 0.38
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
DAO P14920 1/20 0.36
MAP4K4 O95819 1/20 0.35
KCNH2 Q12809 1/20 0.35
SCN3A Q9NY46 1/20 0.35
NFE2L2 Q16236 1/20 0.35
MRGPRX1 Q96LB2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11689102 0.78 CYP3A4 (0.42) PPARGPPARAALDH1A1MAPT
SCHEMBL7867531 0.78 ALDH1A1 (0.49) SLC6A2SLC6A4SLC6A3EGFRERBB2
SCHEMBL7938427 0.77 MAPT (0.46) SLC6A2SLC6A4SLC6A3HTR1AKDM4E
SCHEMBL10695454 0.76 FFAR4 (0.42)
SCHEMBL79800 0.76 LTA4H (0.50) SLC6A2SLC6A4SLC6A3HTR1AKDM4E
SCHEMBL6290410 0.75 ALDH1A1 (0.50) SLC6A2SLC6A4SLC6A3HTR1AKDM4E
SCHEMBL6289878 0.75 ALDH1A1 (0.50) SLC6A2SLC6A4SLC6A3HTR1AKDM4E
SCHEMBL6293224 0.75 ALDH1A1 (0.50) SLC6A2SLC6A4SLC6A3HTR1AKDM4E
SCHEMBL6293197 0.75 ALDH1A1 (0.50) SLC6A2SLC6A4SLC6A3HTR1AKDM4E
SCHEMBL6289927 0.75 ALDH1A1 (0.50) SLC6A2SLC6A4SLC6A3HTR1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0452848-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-10-23 EP disclosed
EP-0138543-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1990-12-27 EP disclosed