Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | ACHE | P22303 | 8/20 | 0.51 |
| ▸ | BCHE | P06276 | 5/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851365 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL11044568 | 0.68 | ADORA2A (0.44) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL11043885 | 0.68 | ADORA2A (0.44) | KDM4EALDH1A1LMNAHPGDGAA | |
| Hydrochloric Acid SCHEMBL29817663 | 0.68 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL8006170 | 0.67 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10286361 | 0.67 | ACHE (0.69) | POLBACHEBCHEGRIN1GRIN2A | |
| SCHEMBL11044466 | 0.67 | KCNH2 (0.44) | KDM4EALDH1A1LMNAHPGDGAA | |
| Hydrochloric Acid SCHEMBL29817811 | 0.66 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL29817833 | 0.66 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL11041195 | 0.66 | TSHR (0.44) | KDM4EALDH1A1LMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |