Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | HPGD | P15428 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045994 | 0.85 | KDM4E (0.88) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL31577611 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL9851362 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL31230012 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL22435548 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL4640583 | 0.71 | HRH4 (0.43) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL11057550 | 0.70 | ACHE (0.67) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL23573722 | 0.69 | KDM4E (0.66) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL2434853 | 0.69 | HRH4 (0.65) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL8006170 | 0.68 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |