SCHEMBL4640583

SCHEMBL4640583

Clc1ccc2nc3c(nc2c1)N(c1ccccc1)CN3c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.43
FGFR1 P11362 1/20 0.43
MAPT P10636 4/20 0.43
NPC1 O15118 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
RAB9A P51151 2/20 0.43
ADORA3 P0DMS8 1/20 0.42
ADORA2A P29274 1/20 0.42
PIK3CG P48736 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
RXFP1 Q9HBX9 1/20 0.41
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 3/20 0.40
GAA P10253 2/20 0.40
LMNA P02545 2/20 0.40
HPGD P15428 2/20 0.40
HCRTR1 O43613 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704624 0.85 MEN1 (0.47) HRH4MAPTNPC1SMN1; SMN2RAB9A
SCHEMBL9705990 0.83 KDM4E (0.46) HRH4MAPTNPC1SMN1; SMN2RAB9A
SCHEMBL9463960 0.82 KDM4E (0.49) HRH4MAPTNPC1SMN1; SMN2RAB9A
SCHEMBL4640523 0.75 HRH4 (0.50) HRH4MAPTSMN1; SMN2KMT2AKDM4E
SCHEMBL29856205 0.72 NQO2 (0.56) MAPTNPC1SMN1; SMN2RAB9APIK3CG
SCHEMBL5157721 0.72 NQO2 (0.56) MAPTNPC1SMN1; SMN2RAB9APIK3CG
SCHEMBL31577611 0.72 KDM4E (0.60) HRH4MAPTNPC1SMN1; SMN2RAB9A
SCHEMBL9851365 0.71 KDM4E (0.72) MAPTNPC1SMN1; SMN2ADORA3ADORA2A
SCHEMBL5157381 0.70 PIK3CG (0.58) HRH4MAPTPIK3CGMEN1KMT2A
SCHEMBL11596282 0.69 NQO2 (0.65) MAPTNPC1SMN1; SMN2RAB9APIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142545-A LASER DYE LAMBDA PHYSIK GESELLSCHAFT ZUR HERSTELLUNG VON LASERN MBH (DE) 1992-08-25 US claimed
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-6756177-B2 MULTICOLOR RECORDING FUJI PHOTO FILM CO., LTD. (JP) 2004-06-29 US disclosed
US-6740466-B1 HIGH SENSITIVITY TO UV, VISIBLE, ANDINFRARED; FOGGING OF THE BACKGROUND IS REDUCED; CLARITY AND HIGH CONTRAST; ADDITION POLYMERIZABLE COMPOUND, AN INDOLE-PYRIMIDINETRIONE METHINE DYE, AN ANIONIC ORGANOBORON COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2004-05-25 US disclosed
US-20030129521-A1 Photopolymerizable composition and recording material FUJI PHOTO FILM CO., LTD. 2003-07-10 US disclosed
EP-1298490-A2 Photopolymerizable composition and recording material Fuji Photo Film Co., Ltd. (JP) 2003-04-02 EP disclosed
US-5578414-A CYANINE DYE, ONIUM SALT, AND HYDRAZINE COMPOUND; HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 1996-11-26 US disclosed
US-5547828-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JP) 1996-08-20 US disclosed
EP-0296873-B1 DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-08 EP disclosed
US-5187049-A Spectral sensitizing dye and salt formed from leuco dye and oxidizing acid MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-02-16 US disclosed
US-4095981-A Photographic material containing an energy-sensitive organic o-nitroarylidene dye and physical development process of forming an image with said material EASTMAN KODAK COMPANY (US) 1978-06-20 US disclosed
US-4081279-A Photothermographic materials containing radiation sensitive quinone compounds and nitrobenzylidene dyes EASTMAN KODAK COMPANY (US) 1978-03-28 US disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4066403-A DECOMPOSITION, PERMEABLE BARRIERS EASTMAN KODAK COMPANY (US) 1978-01-03 US disclosed
US-4035190-A 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-07-12 US disclosed
US-4028113-A Photographic supports and elements utilizing photobleachable O-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1977-06-07 US disclosed
US-4025347-A Fogged direct-positive silver halide emulsion containing a cyanine dye having an indole or indolenine nucleus substituted with a benzoyl or a phenylsulfonyl group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-05-24 US disclosed
US-3988154-A Photographic supports and elements utilizing photobleachable omicron-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed
US-3988156-A Photographic supports and elements utilizing photobleachable o-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed
US-3984248-A Photographic polymeric film supports containing photobleachable o-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-05 US disclosed