Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.48 |
| ▸ | BCHE | P06276 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851360 | 0.85 | ACHE (0.51) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| SCHEMBL9851341 | 0.78 | ALDH1A1 (0.62) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| SCHEMBL4491778 | 0.74 | ALDH1A1 (0.61) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9851357 | 0.73 | ALDH1A1 (0.60) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| SCHEMBL9851342 | 0.72 | KMT2A (0.62) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5579198 | 0.71 | KDM4E (0.85) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| SCHEMBL1110808 | 0.70 | ALDH1A1 (0.73) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| SCHEMBL9851389 | 0.69 | KMT2A (0.47) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| SCHEMBL9851398 | 0.69 | ACHE (0.52) | ACHEKMT2AKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9851346 | 0.68 | KMT2A (0.60) | ACHEBCHEKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |