Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | CLPP | Q16740 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851342 | 0.87 | KMT2A (0.62) | KMT2AMEN1NPC1RXFP1GRIN1 | |
| SCHEMBL9851360 | 0.85 | ACHE (0.51) | KMT2AMEN1ACHEBCHEKDM4E | |
| Hydrochloric Acid SCHEMBL9851346 | 0.83 | KMT2A (0.60) | KMT2AMEN1NPC1RXFP1GRIN1 | |
| SCHEMBL9851398 | 0.75 | ACHE (0.52) | KMT2AMEN1NPC1RXFP1GRIN1 | |
| SCHEMBL9851341 | 0.73 | ALDH1A1 (0.62) | KMT2AMEN1GRIN1GRIN2AACHE | |
| Hydrochloric Acid SCHEMBL5578403 | 0.72 | KDM4E (0.55) | KMT2AMEN1NPC1RXFP1GRIN1 | |
| SCHEMBL9851350 | 0.71 | ACHE (0.61) | KMT2AMEN1NPC1RXFP1GRIN1 | |
| SCHEMBL4491778 | 0.70 | ALDH1A1 (0.61) | KMT2AMEN1GRIN1GRIN2AACHE | |
| SCHEMBL9851336 | 0.69 | MEN1 (0.68) | KMT2AMEN1NPC1RXFP1GRIN1 | |
| SCHEMBL9851378 | 0.69 | ACHE (0.48) | KMT2AMEN1ACHEBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |