Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851333 | 0.78 | ACHE (0.61) | ACHEMEN1NPC1KMT2ARXFP1 | |
| SCHEMBL9851349 | 0.76 | ACHE (0.55) | ACHEMEN1NPC1KMT2ARXFP1 | |
| SCHEMBL9851398 | 0.74 | ACHE (0.52) | ACHEMEN1NPC1KMT2ARXFP1 | |
| SCHEMBL9851343 | 0.70 | ACHE (0.51) | ACHEMEN1NPC1KMT2ARXFP1 | |
| SCHEMBL9583084 | 0.70 | ACHE (1.00) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL8019759 | 0.70 | ACHE (0.94) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL24011117 | 0.70 | NOTUM (0.82) | NOTUMKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9583887 | 0.69 | ACHE (0.97) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| Water SCHEMBL9851375 | 0.68 | ACHE (0.45) | ACHEMEN1NPC1KMT2ARXFP1 | |
| SCHEMBL9851387 | 0.68 | KDM4E (0.53) | ACHEMEN1KMT2AGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |