Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851398 | 0.76 | ACHE (0.52) | ACHEKDM4EALDH1A1LMNAGRIN1 | |
| SCHEMBL9851349 | 0.75 | ACHE (0.55) | ACHEKDM4EALDH1A1LMNABCHE | |
| SCHEMBL9851396 | 0.73 | ACHE (0.55) | ACHEKDM4EMITFALDH1A1LMNA | |
| SCHEMBL9851392 | 0.70 | ACHE (0.53) | ACHEKDM4EALDH1A1LMNABCHE | |
| SCHEMBL9583084 | 0.69 | ACHE (1.00) | ACHEKDM4EALDH1A1LMNABCHE | |
| Hydrochloric Acid SCHEMBL9851361 | 0.68 | ALDH1A1 (0.49) | ACHEKDM4EMITFALDH1A1LMNA | |
| SCHEMBL9851350 | 0.67 | ACHE (0.61) | ACHEKDM4EALDH1A1LMNABCHE | |
| Hydrochloric Acid SCHEMBL9851346 | 0.67 | KMT2A (0.60) | ACHEKDM4EALDH1A1LMNABCHE | |
| SCHEMBL8019759 | 0.66 | ACHE (0.94) | ACHEKDM4EALDH1A1LMNABCHE | |
| SCHEMBL9851342 | 0.64 | KMT2A (0.62) | ACHEKDM4EALDH1A1LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |