Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.55 |
| ▸ | AGT | P01019 | 2/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851410 | 0.93 | AGTR1 (0.64) | AGTR1AGTR2AGTPPARG | |
| SCHEMBL9851445 | 0.90 | AGTR1 (0.53) | AGTR1AGTR2AGTEDNRABRD4 | |
| SCHEMBL9851481 | 0.86 | AGTR1 (0.54) | AGTR1AGTR2AGTBRD4 | |
| SCHEMBL9851520 | 0.82 | AGTR1 (0.57) | AGTR1AGTR2AGT | |
| SCHEMBL9851472 | 0.81 | AGTR1 (0.63) | AGTR1AGTR2AGTPPARG | |
| SCHEMBL9402029 | 0.80 | AGTR1 (0.59) | AGTR1AGTR2AGTRAB9A | |
| SCHEMBL9851487 | 0.80 | AGTR1 (0.63) | AGTR1AGTR2AGTPPARG | |
| SCHEMBL9851456 | 0.80 | AGTR1 (0.52) | AGTR1AGTR2AGTBRD4P2RX7 | |
| SCHEMBL9851514 | 0.79 | AGTR1 (0.60) | AGTR1AGTR2AGTPPARG | |
| SCHEMBL8392437 | 0.79 | AGTR1 (0.60) | AGTR1AGTR2AGTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |