Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847983 | 0.86 | EPHX1 (0.33) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL9847927 | 0.85 | CYP2D6 (0.37) | CYP2D6CYP2C9HIF1APTPN5MEN1 | |
| SCHEMBL9862027 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL9847989 | 0.79 | LMNA (0.38) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL8762517 | 0.78 | CYP2C9 (0.41) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL8853450 | 0.76 | CYP2D6 (0.38) | HTTCYP2D6CYP2C9HIF1ARAB9A | |
| SCHEMBL4224938 | 0.76 | CYP2D6 (0.38) | CYP2D6CYP2C9HIF1APTPN5 | |
| SCHEMBL8972312 | 0.76 | CYP2D6 (0.40) | SMN1; SMN2CYP2D6CYP2C9HIF1ARAB9A | |
| SCHEMBL10169477 | 0.74 | LMNA (0.49) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL10482054 | 0.74 | MAPT (0.33) | SMN1; SMN2HIF1AL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422229-A1 | ADHESIVE RESIN COMPOSITION, PREPARATION THEREOF, AND LAMINATE COMPRISING SAME | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-04-17 | — | — | EP | disclosed |