Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851483 | 0.88 | PPARG (0.67) | PPARGAGTR1AGTR2PDE4APDE4B | |
| SCHEMBL9851543 | 0.87 | AGTR1 (0.66) | PPARGAGTR1AGTR2PDE4APDE4B | |
| SCHEMBL9843785 | 0.87 | PDE4A (0.70) | PPARGAGTR1AGTR2PDE4APDE4B | |
| SCHEMBL8872871 | 0.85 | AGTR2 (0.59) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9854367 | 0.82 | PPARG (0.61) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9853635 | 0.82 | PPARG (0.61) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL7851753 | 0.81 | AGTR1 (0.68) | PPARGAGTR1AGTR2 | |
| SCHEMBL9854260 | 0.81 | PPARG (0.63) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9853637 | 0.81 | PPARG (0.74) | PPARGAGTR1AGTR2PDE4APDE4B | |
| SCHEMBL12716740 | 0.81 | PPARG (0.61) | PPARGAGTR1AGTR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |