Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.52 |
| ▸ | METAP1 | P53582 | 3/20 | 0.52 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27597980 | 0.95 | METAP2 (0.49) | METAP2METAP1ANPEPERAP1ERAP2 | |
| SCHEMBL28360416 | 0.83 | ERAP1 (0.50) | METAP2METAP1ANPEPERAP1ERAP2 | |
| SCHEMBL16755256 | 0.80 | HCAR2 (0.49) | METAP2METAP1ANPEPERAP1ERAP2 | |
| SCHEMBL1649358 | 0.79 | TDP1 (0.46) | METAP2METAP1TDP1CNR2TSHR | |
| SCHEMBL4744749 | 0.79 | ANPEP (0.46) | METAP2METAP1ANPEPERAP1ERAP2 | |
| SCHEMBL5310603 | 0.75 | ESR1 (0.57) | METAP2METAP1ANPEPERAP1ERAP2 | |
| SCHEMBL28307421 | 0.75 | SLC1A3 (0.50) | METAP2METAP1ANPEPERAP1ERAP2 | |
| SCHEMBL15989107 | 0.74 | TLR2 (0.48) | — | |
| SCHEMBL5848773 | 0.74 | METAP2 (0.65) | METAP2METAP1ANPEPERAP1ERAP2 | |
| SCHEMBL21458090 | 0.74 | METAP2 (0.65) | METAP2METAP1ANPEPERAP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194547-A2 | Stable acetylsalicylic acid and diphenhydramine citrate effervescent composition | MILES LABORATORIES, INC. (US) | 1986-09-17 | — | — | EP | claimed |
| EP-0418564-A1 | Effervescent cold or sinus allergy medicine composition having reduced sodium content | BAYER AG (DE) | 1991-03-27 | — | — | EP | disclosed |
| EP-0194547-A2 | Stable acetylsalicylic acid and diphenhydramine citrate effervescent composition | MILES LABORATORIES, INC. (US) | 1986-09-17 | — | — | EP | disclosed |
| US-4083950-A | DECONGESTANT | MILES LABORATORIES, INC. (US) | 1978-04-11 | — | — | US | disclosed |