Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15989107 | 0.91 | TLR2 (0.48) | MGLLKMT2AFAAHHDAC3 | |
| SCHEMBL10620306 | 0.89 | TLR2 (0.54) | MGLLKMT2AFAAHMAPK1 | |
| SCHEMBL27808219 | 0.83 | HDAC3 (0.51) | TDP1MGLLKMT2AFAAHHDAC3 | |
| SCHEMBL28360416 | 0.81 | ERAP1 (0.50) | ANPEPERAP1ERAP2KMT2AMETAP2 | |
| SCHEMBL16755256 | 0.79 | HCAR2 (0.49) | ANPEPERAP1ERAP2MAPK1METAP2 | |
| SCHEMBL9851494 | 0.79 | METAP2 (0.52) | ANPEPERAP1ERAP2TDP1SMN1; SMN2 | |
| SCHEMBL27741870 | 0.77 | FAAH (0.54) | TDP1MGLLKMT2AFAAHHDAC3 | |
| SCHEMBL28133878 | 0.76 | MGLL (0.48) | TDP1MGLLFAAHLPAR1 | |
| SCHEMBL15989153 | 0.75 | KDM4E (0.49) | KMT2ALTA4H | |
| SCHEMBL27597980 | 0.75 | METAP2 (0.49) | ANPEPERAP1ERAP2TDP1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118423-A1 | COMPOSITIONS AND METHODS FOR TREATING MEDICAL CONDITIONS | COMBINATORX, INCORPORATED (US) | 2008-10-02 | — | — | WO | disclosed |