Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406514 | 0.87 | AGTR1 (0.70) | AGTR1AGTR2PPARG | |
| SCHEMBL9851414 | 0.87 | AGTR1 (0.59) | AGTR1AGTR2PPARG | |
| SCHEMBL9851517 | 0.86 | AGTR1 (0.42) | AGTR1AGTR2PPARG | |
| SCHEMBL9646329 | 0.86 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL9851523 | 0.84 | AGTR1 (0.56) | AGTR1AGTR2PPARG | |
| SCHEMBL9851509 | 0.84 | AGTR1 (0.56) | AGTR1AGTR2PPARG | |
| SCHEMBL9851488 | 0.83 | AGTR1 (0.56) | AGTR1AGTR2PPARG | |
| SCHEMBL8972057 | 0.83 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| SCHEMBL9851407 | 0.83 | AGTR1 (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL7842863 | 0.82 | AGTR1 (0.63) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |