Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851530 | 0.93 | ACHE (0.48) | ACHEL3MBTL3PRMT5NAMPTHDAC3 | |
| SCHEMBL9851511 | 0.83 | DRD3 (0.51) | ACHENAMPT | |
| SCHEMBL9851528 | 0.80 | HTR1A (0.57) | — | |
| SCHEMBL2618044 | 0.75 | ACHE (0.68) | ACHEL3MBTL3HDAC3HDAC4HDAC1 | |
| SCHEMBL8917126 | 0.75 | L3MBTL3 (0.84) | ACHEL3MBTL3HDAC4EPHX1L3MBTL1 | |
| SCHEMBL5188509 | 0.74 | ACHE (0.54) | ACHEL3MBTL3HDAC3HDAC4HDAC1 | |
| Oxalic Acid SCHEMBL8694653 | 0.74 | ACHE (0.57) | ACHEL3MBTL3NAMPTHDAC3HDAC4 | |
| SCHEMBL3459209 | 0.73 | ACHE (0.65) | ACHEL3MBTL3HDAC3HDAC4HDAC1 | |
| SCHEMBL12154736 | 0.73 | ACHE (0.64) | ACHEL3MBTL3HDAC3HDAC4HDAC1 | |
| SCHEMBL13152686 | 0.73 | ACHE (0.64) | ACHEL3MBTL3NAMPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447292-A1 | 4-Aminomethyl-piperidine derivatives, their preparation and therapeutic application | SYNTHELABO (FR) | 1991-09-18 | — | — | EP | disclosed |