Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219929 | 0.76 | ALDH1A1 (0.61) | FEN1PARP1DAODDOCA12 | |
| SCHEMBL9128769 | 0.74 | FEN1 (0.50) | FEN1PARP1DAODDOFFAR1 | |
| SCHEMBL12836459 | 0.74 | FEN1 (0.52) | FEN1PARP1DAODDOFFAR1 | |
| SCHEMBL3106487 | 0.71 | FEN1 (0.50) | FEN1PARP1DAODDOFFAR1 | |
| SCHEMBL29567841 | 0.71 | FEN1 (0.50) | FEN1PARP1DAODDOFFAR1 | |
| Butyric Acid SCHEMBL9251506 | 0.70 | SMN1; SMN2 (0.40) | FEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14843284 | 0.69 | PARP1 (0.49) | FEN1PARP1DAODDOFFAR1 | |
| SCHEMBL24575981 | 0.68 | FEN1 (0.47) | FEN1PARP1DAODDOFFAR1 | |
| SCHEMBL1203402 | 0.68 | F2 (0.52) | FEN1PARP1DAODDOFFAR1 | |
| SCHEMBL7041118 | 0.67 | KDM4E (0.50) | FEN1PARP1DAODDOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424802-A2 | Tricyclic quinoline antineoplastic agents | ABBOTT LABORATORIES (US) | 1991-05-02 | — | — | EP | disclosed |