Butyric Acid

Butyric Acid

SCHEMBL9251506

CCCC(=O)O.Fc1[nH]c2cccc(F)c2c1F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.40
FEN1 P39748 1/20 0.39
GPR17 Q13304 3/20 0.37
FFAR3 O14843 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26693247 0.79 FEN1 (0.46) FEN1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL20119998 0.71 GPR17 (0.49) SMN1; SMN2GPR17KDM4EALDH1A1
Carbazole SCHEMBL4314436 0.70 GABRP (0.55) SMN1; SMN2FFAR3HDAC3HDAC1HDAC2
SCHEMBL9851537 0.70 FEN1 (0.49) SMN1; SMN2FEN1KDM4EALDH1A1
SCHEMBL9192404 0.69 GPR17 (0.71) GPR17KDM4EALDH1A1
SCHEMBL7452457 0.69 GPR17 (0.49) FEN1GPR17KDM4EALDH1A1
Valeric Acid SCHEMBL29009776 0.68 AKR1B1 (0.48) SMN1; SMN2HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL28866266 0.68 FFAR3 (0.48) SMN1; SMN2FFAR3HDAC3HDAC1HDAC2
Butyric Acid SCHEMBL27718388 0.68 KDM4E (0.46) KDM4EALDH1A1MAPK1
Butyric Acid SCHEMBL27907905 0.67 ALDH1A1 (0.53) FEN1FFAR3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114890834-A Plant growth regulator based on trifluoroindole butyric acid 广东农工商职业技术学院 2022-08-12 CN claimed
JP-7184495-A None JP disclosed
CN-114890834-A Plant growth regulator based on trifluoroindole butyric acid 广东农工商职业技术学院 2022-08-12 CN disclosed
CN-114890834-A Plant growth regulator based on trifluoroindole butyric acid 广东农工商职业技术学院 2022-08-12 CN disclosed
CN-108558857-B Thiazole piperidine furanone derivatives and preparation method and application thereof 南开大学 2021-07-02 CN disclosed
CN-108558796-B Hydroxy methylene hydrindone derivatives, preparation method and application thereof 南开大学 2020-04-07 CN disclosed
CN-108675974-B Strigolactone derivatives and preparation method and application thereof 南开大学 2020-04-07 CN disclosed
CN-102241619-A Preparation method of trifluoroindole butyrate and analogues thereof UNIV NORTHEAST AGRICULTURAL 2011-11-16 CN disclosed
CN-102241619-A Preparation method of trifluoroindole butyrate and analogues thereof UNIV NORTHEAST AGRICULTURAL 2011-11-16 CN disclosed
JP-H07184495-A BUDDING MEDIUM AND GROWTH STIMULATION NISSAN CHEM IND LTD 1995-07-25 JP disclosed