Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.63 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13780501 | 0.83 | CES2 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3765957 | 0.83 | MAPT (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11248287 | 0.82 | CES2 (0.69) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30758862 | 0.82 | CES2 (0.69) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28507824 | 0.81 | HSD11B1 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29588852 | 0.81 | CES2 (0.67) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL733307 | 0.81 | CES2 (0.67) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1305114 | 0.81 | CES2 (0.67) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2558590 | 0.80 | CHRM2 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL24262851 | 0.79 | CES2 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428268-A2 | Pharmaceutical phenylpyridone derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-05-22 | — | — | EP | disclosed |