Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MGMT | P16455 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2775956 | 0.99 | PNP (0.42) | PNPSLC2A1CDK1CCNB1CCNA2 | |
| SCHEMBL28061198 | 0.89 | PNP (0.39) | PNPSLC2A1CDK1CCNB1CCNA2 | |
| SCHEMBL22090217 | 0.84 | PNP (0.42) | PNPSLC2A1CDK1CCNB1CCNA2 | |
| SCHEMBL1533592 | 0.82 | SLC2A1 (0.41) | PNPSLC2A1CDK1CCNB1CCNA2 | |
| SCHEMBL6952184 | 0.82 | SLC2A1 (0.41) | PNPSLC2A1CDK1CCNB1CCNA2 | |
| SCHEMBL1533534 | 0.82 | SLC2A1 (0.44) | PNPSLC2A1CDK1CCNB1CCNA2 | |
| SCHEMBL10474536 | 0.78 | SLC2A1 (0.39) | PNPSLC2A1CDK1CCNB1CCNA2 | |
| SCHEMBL27617652 | 0.77 | PNP (0.44) | PNPCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL17186381 | 0.75 | PNP (0.44) | PNPSLC2A1CDK1CCNB1CCNA2 | |
| SCHEMBL18605636 | 0.75 | PNP (0.44) | PNPSLC2A1CDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-08-11 | — | — | US | disclosed |
| US-20140023592-A1 | SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS | RWTH AACHEN (DE) | 2014-01-23 | — | — | US | disclosed |
| EP-2587263-A1 | Self coupling recombinant antibody fusion proteins | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-20110014196-A1 | Drug Transfer into Living Cells | COVALYS BIOSCIENCES AG (CH) | 2011-01-20 | — | — | US | disclosed |
| US-7825096-B2 | O6-alkylguanine-DNA alkyltransferase inactivators and beta-glucuronidase cleavable prodrugs | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-11-02 | — | — | US | disclosed |
| US-7799524-B2 | Substrates for O6-alkylguanina-DNA alkyltransferase | Ecole Polytechnique Ferdeale de Lausanne (CH) | 2010-09-21 | — | — | US | disclosed |
| US-20100183516-A1 | SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2171456-A2 | SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009043899-A1 | DRUG TRANSFER INTO LIVING CELLS | COVALYS BIOSCIENCES AG (CH) | 2009-04-09 | — | — | WO | disclosed |
| WO-2009013359-A2 | SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS | FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) | 2009-01-29 | — | — | WO | disclosed |
| US-20070213279-A1 | O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INACTIVATORS AND BETA-GLUCURONIDASE CLEAVABLE PRODRUGS | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE | 2007-09-13 | — | — | US | disclosed |
| US-20060024775-A1 | Substrates for o6-alkylguanina-dna alkyltransferase | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL). (CH) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110014196-A1 | Drug Transfer into Living Cells | TSPO, MPI, ABCB1 | PNP 112/4885SLC2A1 8/4885CDK1 2503/4885 |
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | EPCAM, IK, TSPO | PNP 4748/4885SLC2A1 761/4885CDK1 2296/4885 |
| US-20060024775-A1 | Substrates for o6-alkylguanina-dna alkyltransferase | AGT, OGG1, NUDT1 | PNP 176/4885SLC2A1 1035/4885CDK1 3650/4885 |
| US-20070213279-A1 | O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INACTIVATORS AND BETA-GLUCURONIDASE CLEAVABLE PRODRUGS | UNG, OGG1, MPG | PNP 20/4885SLC2A1 227/4885CDK1 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.