SCHEMBL9851782

SCHEMBL9851782

C[SiH](C)[C@@]1(n2cnc3c(O)ncnc32)O[C@H](CO)C[C@H]1OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 1/20 0.31
PI4K2B Q8TCG2 1/20 0.31
PI4K2A Q9BTU6 1/20 0.31
PI4KB Q9UBF8 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA2A P29274 1/20 0.31
SLC28A1 O00337 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851702 0.91
SCHEMBL9851849 0.82
SCHEMBL9851800 0.78 PRMT5 (0.31)
SCHEMBL2289573 0.77 PI4KA (0.39) PI4KAPI4K2BPI4K2API4KB
SCHEMBL9851750 0.74
SCHEMBL646508 0.73 ADORA3 (0.42) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL4783246 0.73 PI4KA (0.35) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL30612765 0.73 ADORA3 (0.39) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL9216490 0.72 ADORA1 (0.34) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL9851736 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP claimed
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP disclosed