Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | GMPS | P49915 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218681 | 0.90 | ADORA1 (0.44) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9851800 | 0.82 | PRMT5 (0.31) | — | |
| SCHEMBL4783246 | 0.78 | PI4KA (0.35) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9223640 | 0.76 | — | — | |
| SCHEMBL27825739 | 0.74 | ADORA3 (0.50) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9851750 | 0.73 | — | — | |
| SCHEMBL1140780 | 0.73 | — | — | |
| SCHEMBL9851782 | 0.72 | PI4KA (0.31) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL7893477 | 0.71 | ADORA3 (0.44) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5801879 | 0.70 | DNPH1 (0.44) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455339-A | Method for the preparation of 2',3'-dideoxy and 2',3'-dideoxydide-hydro nucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-10-03 | — | — | US | disclosed |