Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATG7 | O95352 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851822 | 0.93 | MAPT (0.44) | MAPTHSPA5PDE2AHTR1ATYMP | |
| SCHEMBL9851724 | 0.91 | MEN1 (0.49) | MAPTTYMPMEN1KMT2A | |
| SCHEMBL9851718 | 0.91 | HSPA5 (0.48) | MAPTHSPA5PDE2ATYMPMEN1 | |
| SCHEMBL9851826 | 0.86 | MEN1 (0.47) | MAPTTYMPMEN1KMT2AATG7 | |
| SCHEMBL9851722 | 0.85 | MAPT (0.47) | MAPTHTR1ATYMPMEN1KMT2A | |
| SCHEMBL9851711 | 0.80 | MAPT (0.45) | MAPTPDE2ATYMPMEN1KMT2A | |
| SCHEMBL9851703 | 0.80 | MAPT (0.44) | MAPTPDE2AHTR1ATYMPMEN1 | |
| SCHEMBL9851884 | 0.78 | ATG7 (0.43) | MAPTTYMPMEN1KMT2AATG7 | |
| SCHEMBL9851809 | 0.76 | MAPT (0.46) | MAPTMEN1KMT2A | |
| SCHEMBL11672852 | 0.75 | HSPA5 (0.49) | HSPA5PDE2AHTR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | disclosed |