Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851703 | 0.88 | MAPT (0.44) | MAPTLMNATYMPHRH4HRH3 | |
| SCHEMBL9851738 | 0.84 | STING1 (0.40) | MAPTLMNATYMPNT5ESTING1 | |
| SCHEMBL9851718 | 0.83 | HSPA5 (0.48) | MAPTTYMPNT5EMEN1KMT2A | |
| SCHEMBL9851714 | 0.82 | ALDH1A1 (0.43) | MAPTLMNANT5ESTING1MEN1 | |
| SCHEMBL9851855 | 0.82 | NT5E (0.37) | MAPTLMNATYMPNT5ESTING1 | |
| SCHEMBL9851809 | 0.81 | MAPT (0.46) | MAPTLMNASTING1MEN1KMT2A | |
| SCHEMBL9851796 | 0.80 | MAPT (0.44) | MAPTTYMPMEN1KMT2APDE2A | |
| SCHEMBL9851822 | 0.80 | MAPT (0.44) | MAPTTYMPNT5EMEN1KMT2A | |
| SCHEMBL9851804 | 0.80 | NT5E (0.41) | MAPTLMNATYMPNT5ESTING1 | |
| SCHEMBL9851876 | 0.76 | NT5E (0.40) | MAPTLMNATYMPNT5ESTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | disclosed |