Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 4/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.35 |
| ▸ | MERTK | Q12866 | 5/20 | 0.35 |
| ▸ | AXL | P30530 | 4/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851703 | 0.91 | MAPT (0.44) | MAPTMEN1KMT2AIP6K1ALDH1A1 | |
| SCHEMBL9851757 | 0.83 | ALDH1A1 (0.40) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9851820 | 0.83 | ALDH1A1 (0.39) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9851722 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2AIP6K1ALDH1A1 | |
| SCHEMBL9851826 | 0.81 | MEN1 (0.47) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9851711 | 0.81 | MAPT (0.45) | MAPTMEN1KMT2AIP6K1LMNA | |
| SCHEMBL9851724 | 0.81 | MEN1 (0.49) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9851856 | 0.79 | ALDH1A1 (0.39) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9851714 | 0.79 | ALDH1A1 (0.43) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9851837 | 0.76 | ALDH1A1 (0.35) | MAPTALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | disclosed |